Petsmile Dog toothpaste 4.5oz, Duck Flavor, Backed by powerful clinical results, Petsmile is the first Veterinary Oral Health Council (VOHC) awarded toothpaste for plaque inhibition. Plaque on your pet’s teeth can lead to cavities, tartar build-up, bleeding gums, and oral disease. Formulated with our proprietary Calprox ingredient, Petsmile effectively removes plaque and has been clinically demonstrated to provide a 62% greater reduction in plaque versus a control toothpaste.